Current Issue : January-March Volume : 2013 Issue Number : 1 Articles : 12 Articles
The study was aimed to evaluation of the anticancer activity of the leaves of Arjuna (Terminalia arjuna) is a widespread medicinal plant used in the AYURVEDIC system of medicine to care for various active ingredients now used for herbal formulations. Terminalia arjuna leaves, (polyphenols) anticancer activity study has been restricted that''s why in the present study we have addressed and provides an impression of extraction, photochemical analysis, flavonoide quantification, FTIR analysis anticancer activity MTT Assay of terminalia arjuna leaves. From this it may conclude that Terminalia arjuna leaves shows effective cytotoxicity on A549>MCF7>PA respective cell line....
To evaluate antihistaminic, antiallergic and mast cell stabilizing effect of phytosterol rich fractions of Leptadenia reticulata (Retz) in various experimental models. In the present study The Unsaponifiable matter (LRUSM) from petroleum extract, acetone (LRA), and methanol (LRM) fraction of the aerial parts of Leptadenia reticulata (Retz) Wight and Arn. (Asclepiadaceae) were studied for Antihistaminic, antiallergic and mast cell stabilizing effect were studied on the Histamine aerosol induced anaphylactic shock induced bronchospasm in guinea pigs. Cows Milk induced eosinophilia in mice, and Clonidine induced mast cell degranulation in rats in the animal model. Treatment with unsaponifiable matter (LRUSM) and LRM treated groups resulted significant protection (P< 0.001) against histamine aerosol-induced bronchospasm in guinea pigs. LRUSM and LRM showed significant Dose dependent (50 &100 mg/kg p.o) decrease in no of eosinophils count and also reduced clonidine induced mast cell degranulation in rats, L. reticulata showed significant decrease in no. of degranulated mast cells count and significant increase in no. of intact mast cells count induced mast cell degranulation in rats. Antihistaminic, antiallegic activity aerial part of Leptadenia reticulata may be possibly due to the membrane stabilising potential, suppression of antibody production and inhibition of antigen induced histamine, suppression of IgE antibody production, due to compound like carbohydrate, glycosides, flavonoids, tannins, phytosterols like �Ÿ-sitosterol, stigmasterol, in LRUSM , Phenolic compounds in acetone(LRA) and methanolic extracts(LRM) of aerial part Leptadenia reticulata(Retz)....
According to ayurvedic texts shodhan vidhi is an important process which enhances the biological activity of a compound and reduces the toxicity at the same time. The seeds of Abrus precatorious (leguminosae) known as chanothi were processed as prescribed in the Ayurvedic classics. The seeds were soaked in cow urine (7 days) and roasted in cow ghee (till swollen) to make it shodhit. The processed seeds were compared with an untreated sample to assess the effect of processing on toxicity profile and anti-inflammatory action. The anti-inflammatory activity was checked by carragenan induced rat paw oedema model. Pre-treatment with the extract (250 - 500 mg/kg, p.o.) significantly prevented increase in volume of paw oedema in dose dependent manner. A maximal effect was observed at 500 mg/kg which was comparable to diclofenac (20 mg/kg, orally). It was observed that the different shodhit seeds i.e. processed using different Shodhan vidhi, showed good anti-inflammatory activity as compared to Ashudha seeds and also the toxicity profile reduced greatly. Thus Shodhan vidhi enhances the therapeutic properties of Abrus precatorious seeds....
India is considered as Golden bird in terms of rich diversity of medicinal plants it posses. Since ages, hundreds of tribals residing in and around forests have acquired valuable information of the plants of healing property or value to human health. These also include knowledge on plant parts such as barks, roots, leaves, flowers and fruits possessing individualistic and high medicinal properties. One such versatile vital plant Ficus racemosa Linn. include two main leucoanthocyanins, leucocyanidin-3-O-β-glucopyranoside, leucopelarogonidin-3-O-α-L-rhamnopyranoside, β-sitosterol, long chain ketones, ceryl behenate, lupeol, lupeol acetate, α-amyrin acetate, glauanol, hentriacontane, tiglic acid, esters of taraxasterol, friedelin, phytosterol, tetracyclic triterpenes glauanol acetate. The present review is an effort to concise the properties and explored potential to the medicinal world, of this imperative plant....
In this study, In-vitro antioxidant activity of hexane (PAHE), ethyl acetate (PAEA), methanolic (PAME) extracts and isolated lignans (phyllanthin (PAPH) & hypophyllanthin (PAHP)) of P.amarus aerial parts was investigated by using Superoxide radical, Hydroxyl radical and DPPH radical scavenging methods. Phyllanthus amarus Schum. & Thonn. is a small herb well known for its medicinal properties. P. amarus is an important plant of Indian Ayurvedic system of medicine for treatment of several ailments. The tested extracts and isolated lignans showed dose dependent inhibition of in vitro free radical generation of superoxide anion, hydroxyl radical and DPPH radicals. The results clearly indicated the free radical scavenging activity of tested extracts and lignans of P.amarus aerial parts, this activity is comparable with that of the standard drug ascorbic acid....
General phytochemical screening of the aerial parts of Leptadenia reticulata (Retz) Wight and Arn. (Asclepiadaceae) revealed the presence of steroids, terpenes, phenolic compounds, saponins, fatty acids, Flavonoids. The aim of this study is to identify and characterize the bioactive principle from the aerial parts of the plant. It has wide folk medicinal use. For isolation of the compound, the dried aerial parts powder of Leptadenia reticulata was subjected to hot extraction with petroleum ether this extract was saponified with alcoholic KOH and the unsaponifiable matter (LRUSM) from petroleum extract was subjected to column chromatography. Isolated compound were purified by chloroform. The isolation and purification afforded white crystalline powder which was subjected to physical, chemical and spectral identification by IR, 1H‐NMR, 13C‐NMR and GC‐MS. From the above physical, chemical and spectral evidences, the compounds isolated from unsaponifiable matter of the aerial parts Leptadenia Reticulata is confirmed as Campetstrol and β-sitosterol. They were isolated and chemical structures elucidated respectively. It was carried out by means of various physic chemical method, solvent extraction, HPTLC, Column chromatography and spectral hypanated techniques GC-MS study....
Caesalpinia bonducella (L.) Fleming (family caesalpiniaceae), commonly known as Nata Karanja, is a prickly shrub widely distributed all over the world specially, in India. All parts of the plant have medicinal properties so it is a very valuable medicinal plant which is utilized in traditional system of medicine. The plant has been reported to possess anxiolytic, antinociceptive, antidiarrhoeal and antifilarial activities. Although the parts are utilized medicinally, pharmacognostical study of the plant part seed is not reported. Hence, seed of the plant were evaluated for its macroscopical, microscopical and phytochemical parameters. The result revealed that plant is authentic as per the pharmacopoeial standards....
Trigonella foenum graecum Linn. (family Fabaceae), commonly known as Fenugreek is a aromatic, 30-60 cm tall, annual herb, cultivated throughout the country. The seeds are hot, with a sharp bitter taste, tonic, antipyretic, anthelmentic, increase the appetite, astringent to the bowels, cure leprosy, vomiting, bronchitis, piles, remove bad taste from the mouth, useful in heart disease. Although the parts are utilized medicinally, pharmacognostical study of the plant part seed is not reported. Hence, seed of the plant were evaluated for its macroscopical, microscopical and phytochemical parameters. The result revealed that plant is authentic as per the pharmacopoeial standards....
The present work is aimed at investigating the pharmacognostical characters of the aerial parts of Calotropis gigantea. Calotropis gigantea is commonly available throughout the plains of India. Along with its close relative, C. procera, it is used in Indigenous systems of medicine as well as in home remedies and tribal medicine. It is reported that both the plants used vis-à-vis or get inter-changed or used as alternative to one another or get confused with common people and even in some literature. They are economically important, produces more durable quality fiber, which may also be used even for cloth weaving, latex for tanning, wood as fuel, hairs to fill pillows and many other uses, apart from its cultural and medicinal importance. All parts of C. gigantea are used in medicine either as whole or as individual parts for various ailments. Leaves, flowers, root and root bark are used in Ayurveda. Leaves, flowers, roots and latex are used in Siddha. Medicinal properties of C. procera are very similar to C. gigantea. Available pharmacognostical studies on C. gigantea are fragmented. Pharmacognostical studies on roots, leaves and flowers are available separately. Though the aerial parts are also used in some ailments, and also a commercially available crude drug, pharmacognostical characters of aerial parts of C. gigantea is not available. Characters to differentiate the aerial parts of C. gigantea with C. procera as market sample, is also not available. This article fulfills the pharmacognostical characteristic features of aerial parts of C. gigantea and narrates the characters to differentiate C. procera in commercially available market samples. It is observed that non-lignified pericyclic fibers in stem, bicollateral vascular bundles, stomata on both surfaces, starchy endodermis, and soft, shaggy & tangled trichomes, are the diagnostic characters of C. gigantea. Though the macroscopical and microscopical characters are more or less similar in both the species, 4 rows of palisade cells and abundant starch in stem pith and little wide lumen in pericyclic fibers are the diagnostic characters, which differentiate C. procera from C. gigantea....
The reliability and integrity of traditional systems of medicine depend upon properly identified sample of drugs ready to use as therapeutic agents for safety reason of the consumers. Keeping this background in mind, basically a folklore drug also used in Unani Medicine and Ayurveda, the present study gives insight into the anatomical, pharmacognosy, histochemical and preliminary phytochemical analysis of the bark of Ficus Racemosa linn. The analyses were done according to WHO norms. Pharmacognostic parameters such as morphology, anatomy, macrometry, micrometry, physicochemical evaluation, preliminary phytochemical evaluation and fluorescence analysis of bark were carried out using standard methods. TLC of aqueous and methanol extracts of bark were also made. Detailed results have been shown in figures and tables. The study provided useful information which can effectively be used to ascertain the authenticity of the available sample of the drug....
The seeds of Nigella sativa (N.sativa) Linn. (Ranunculaceae) are used commonly in the Middle East as a traditional medicine to treat variety of health conditions and has health promoting properties. In present investigation petroleum ether (PEE) and ethanolic extract (EE) of N. sativa seeds were evaluated. On the basis of their physiochemical characters and antioxidant potential. Both extract were found to possess significant antioxidant activity against DPPH free radical. IC50 for PEE was 54.2 µg/ml and for EE was 71.2 µg/ml. Ethanolic extract was having significant quantity of phenolic and flavonoid components, this was confirmed on the basis of TPC (67.45 µg/mg extract GAE) and TFC (74 µg/mg extract RE) test. Thus from present study it can be concluded that pet ether extract and ethanolic extract of N. sativa are good antioxidants and would be a good alternative for diseases related to oxidative stress....
Moringa oliefera Lam. or Moringa pterygosperma is one of the best known and most widely distributed and naturalized species of a monogenetic family Moringaceae. It is a small or middle sized tree, which is cultivated throughout India. The fruit of this tree is edible and constitutes one of the common vegetable dishes in India. Seed oil is known to be useful in treatment of leprous ulcers. Various parts of the M. oleifera tree have been studied for several pharmacological actions. Although the parts are utilized medicinally, pharmacognostical study of the plant part seed is not reported. Hence, seed of the plant were evaluated for its macroscopical, microscopical and phytochemical parameters. Macroscopical and microscopical investigations revealed that the plant was authentic as per the pharmacopoeial standards. Phytochemical investigation of seed shows foreign matter (0.70 gm/100 gm), pH (5.4), loss on drying is (6.5 mg/gm), total ash (4.81%), acid insoluble ash (0.70%), water soluble ash (2.10%), Sulphated ash (3.88%), water soluble extractive value (32.8%) and alcohol soluble extractive value (37.0%). The results of phytochemical investigations revealed that plant is authentic as per the pharmacopoeial standards....
Loading....